2014) Analysis of the linker area becoming a member of the adenylation and provider protein domains of the modular nonribosomal peptide synthetases. 2006) Structure of the EntB multidomain nonribosomal peptide synthetase and practical analysis of its interplay with the EntE adenylation domain. 1991) Expression of tandem glutathione S-transferase recombinant genes in COS cells for analysis of efficiency of protein expression and associated drug resistance. 1997) High-stage production and purification of biologically energetic proteins from bacterial and mammalian cells using the tandem pGFLEX expression system. 1997) Molecular constructions of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli. Gulick AM, Rayment I. (1997) Structural research on myosin II: communication between distant protein domains. Gulick AM. (2009) Conformational dynamics within the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase. 2018) Trapping interactions between catalytic domains and provider proteins of modular biosynthetic enzymes with chemical probes. 2014) Structural and bioinformatic characterization of an Acinetobacter baumannii sort II provider protein.
2013) Non-Nucleoside Inhibitors of BasE, an Adenylating Enzyme in the Siderophore Biosynthetic Pathway of the Opportunistic Pathogen Acinetobacter baumannii. 1995) Mammalian glutathione S-transferase: regulation of an enzyme system to realize chemotherapeutic efficacy. 2010) Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis. 2016) Structural and Purposeful Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae. 2019) Construction of a certain peptide phosphonate reveals the mechanism of nocardicin bifunctional thioesterase epimerase-hydrolase half-reactions. Gulick AM. (2016) Structural perception into the necessary conformational changes of modular nonribosomal peptide synthetases. 2016) 1.2 Å decision crystal structure of the periplasmic aminotransferase PvdN from Pseudomonas aeruginosa. 2007) The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa. Wu R, Reger AS, Cao J, Gulick AM, Dunaway-Mariano D. (2007) Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate vary.
1992) Mutational substitution of residues implicated by crystal structure in binding the substrate glutathione to human glutathione S-transferase pi. Gulick AM, Palmer DR, Babbitt Pc, Gerlt JA, Rayment I. (1998) Evolution of enzymatic actions within the enolase superfamily: crystal construction of (D)-glucarate dehydratase from Pseudomonas putida. Gulick AM, Lu X, Dunaway-Mariano D. (2004) Crystal construction of 4-chlorobenzoate:CoA ligase/synthetase within the unliganded and aryl substrate-sure states. 2008) Structural characterization of a 140 levels domain movement in the 2-step response catalyzed by 4-chlorobenzoate:CoA ligase. 2015) The construction of S. lividans acetoacetyl-CoA synthetase reveals a novel interplay between the C-terminal extension and the N-terminal domain. Demonte D, Drake EJ, Lim KH, Gulick AM, Park S. (2013) Structure primarily based engineering of streptavidin monomer with a reduced biotin dissociation rate. Demonte D, Drake EJ, Lim KH, Gulick AM, Park S. (2013) Structure-based engineering of streptavidin monomer with a reduced biotin dissociation price. Gulick AM, Hubbard BK, Gerlt JA, Rayment I. (2001) Evolution of enzymatic actions within the enolase superfamily: identification of the general acid catalyst in the energetic site of D-glucarate dehydratase from Escherichia coli. Manoharan TH, Welch PJ, Gulick AM, Puchalski RB, Lathrop AL, Fahl WE. Kholodar SA, Tombline G, Liu J, Tan Z, Allen CL, Gulick AM, Murkin AS. Wang Y, Feng L, Said M, Balderman S, Fayazi Z, Liu Y, Ghosh D, Gulick AM. Gulick AM. (2009) Ironing out a brand new siderophore synthesis strategy.
Wu R, Cao J, Lu X, Reger AS, Gulick AM, Dunaway-Mariano D. (2008) Mechanism of 4-chlorobenzoate:coenzyme a ligase catalysis. Patel KD, d’Andrea FB, Gaudelli NM, Buller AR, Townsend CA, Gulick AM. Gulick AM, Starai VJ, Horswill AR, Homick KM, Escalante-Semerena JC. Miller BR, Drake EJ, Shi C, Aldrich CC, Gulick AM. Bailey DC, Alexander E, Rice MR, Drake EJ, Mydy LS, Aldrich CC, Gulick AM. Bailey DC, Drake EJ, Grant TD, Gulick AM. Mitchell CA, Tucker AC, Escalante-Semerena JC, Gulick AM. Manoharan TH, Gulick AM, Puchalski RB, Servais AL, Fahl WE. Thoden JB, Gulick AM, Holden HM. Drake EJ, Miller BR, Shi C, Tarrasch JT, Sundlov JA, Allen CL, Skiniotis G, Aldrich CC, Gulick AM. Sundlov JA, Garringer JA, Carney JM, Reger AS, Drake EJ, Duax WL, Gulick AM. Wurst JM, Drake EJ, Theriault JR, Jewett IT, VerPlank L, Perez JR, Dandapani S, Palmer M, Moskowitz SM, Schreiber SL, Munoz B, Gulick AM.